Abnormal accumulation of amyloid in an organ or tissue.
What is Amyloidosis?
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Amyloid deposits in the three major compartments of the kidney: A: Glomerular amyloid deposits predominantly in mesangial spaces (400x, red arrow). B: Interstitial amyloidosis (200x). C: Vascular amyloidosis (100x). D: Congo Red stain of vascular amyloid deposits (100x). A-C are H&E stained sections. Comparison of amyloid deposition in human kidney biopsies as a predictor of poor patient outcome: Castano E, Palmer MB, Vigneault C, Luciano R, Wong S, Moeckel G - BMC nephrology (2015). Not altered. CC.