Asplenia is a disorder categorized with the anatomical absence of the spleen tissue. Asplenia stereotypically occurs in connotation with situs ambiguous also known as heterotaxia. Asplenia can be acquired or iatrogenic.
What is Asplenia?

Asplenia. A 22-week fetus with asplenia syndrome. Fetal CMR B-TFE four-chamber view image shows the small left ventricle (arrow) and complete atrioventricular septal defect (open arrow). MR imaging of fetal cardiac malposition and congenital cardiovascular anomalies on the four-chamber view. Dong SZ, Zhu M - SpringerPlus (2016). Not Altered. CC.