What is Basal Cell Carcinoma?

Basal Cell Carcinoma
Basal Cell Carcinoma. Indolent-growth histologic subtypes [64]. a) Nodular basal cell carcinoma: Medium-power view of a section of eyelid showing both the cutaneous surface at the top and the conjunctiva in the lower inked portion. Nodular basal cell carcinoma is present throughout the dermis. Note the large, nodular aggregates of dark-blue-staining basaloid keratinocytes showing peripheral palisading and clefting. b) Superficial basal cell carcinoma: Medium-power view of superficial basal cell carcinoma, showing basaloid aggregates emanating from the epidermis and growing along an axis parallel to the epidermis. Peripheral palisading and clefting is present. Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management: Marzuka AG, Book SE - The Yale journal of biology and medicine (2015). Not altered. CC.

Basal cell carcinoma is a malignant epidermal tumor that affects the basement membrane of epithelial cells.

What is the Pathology of Basal Cell Carcinoma?

The pathology of basal cell carcinoma is  Forms strands, cords and island of tumor appearing similar to the normal epithelial basal layer.

How does Basal Cell Carcinoma Present?

Basal cell carcinoma presents with   Pearly appearance, crusting, telangiectasia, erosion or ulceration.

How is Basal Cell Carcinoma Diagnosed?

Basal cell carcinoma is diagnosed by  assessment of ocular motility, assessment for proptosis, assessment of madarosis, assessment of eyelid malposition, incisional or excisional tissue biopsy.

How is Basal Cell Carcinoma Treated?

Basal cell carcinoma is treated with  administration of Vismodegib, topical imiquimod 5% cream, surgical excision, sonidegib, intron-A, efudex, tazarotene, PD1-inhibitor.

What is the Prognosis of Basal Cell Carcinoma?

The prognosis of basal cell carcinoma is a 5 years cure rate. Prognosis gets worse with deeply invasive tumors, inadequate treatment, long-standing lesions, lesions greater than 3 cm.