What is Basal Cell Carcinoma?

Basal Cell Carcinoma
Basal Cell Carcinoma. Indolent-growth histologic subtypes [64]. a) Nodular basal cell carcinoma: Medium-power view of a section of eyelid showing both the cutaneous surface at the top and the conjunctiva in the lower inked portion. Nodular basal cell carcinoma is present throughout the dermis. Note the large, nodular aggregates of dark-blue-staining basaloid keratinocytes showing peripheral palisading and clefting. b) Superficial basal cell carcinoma: Medium-power view of superficial basal cell carcinoma, showing basaloid aggregates emanating from the epidermis and growing along an axis parallel to the epidermis. Peripheral palisading and clefting is present. Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management: Marzuka AG, Book SE - The Yale journal of biology and medicine (2015). Not altered. CC.

Basal cell carcinoma is a nonmelanocytic skin tumor arising from basal cells.

What is the Pathology of Basal Cell Carcinoma?

The pathology of basal cell carcinoma is:

-Etiology: The cause of basal cell carcinoma is radiation exposure, gene mutations, immunosuppression, idiopathic.

-Genes involved: TP53 gene.

-Pathogenesis: The sequence of events that lead to basal cell carcinoma are due to pluripotential cells of the basal layer of the epidermis/follicular that are abnormal.

-Morphology: The morphology associated with basal cell carcinoma shows a scale, erythema, and a threadlike raised border.

-Histology: The histology associated with basal cell carcinoma shows large, hyperchromatic, little cytoplasm, and oval nuclei basalioma cells.

How does Basal Cell Carcinoma Present? 

Patients with basal cell carcinoma typically common in males present at an age range of 55-70 years. The symptoms, features, and clinical findings associated with basal cell carcinoma include slowly widening lesions, waxy papules, ulceration, with crusting that bleed when injured.

How is Basal Cell Carcinoma Diagnosed? 

Basal cell carcinoma is diagnosed through the clinical presentation.

How is Basal Cell Carcinoma Treated? 

Basal cell carcinoma is treated through surgery, chemotherapeutic.

What is the Prognosis of Basal Cell Carcinoma?

The prognosis of basal cell carcinoma is good with a 100% survival rate for those that have not spread.

Tags:
Last updated on May 22, 2022