Bone pathology of the iliac crest in a 17-year-old patient with MPS IVA after clinical trial.Notes: Left panel: 6 months extension study of ERT (toluidine blue-stained 0.5- μm-thick sections: ×100). Right panel: 8-year-old male control (chondrocytes in a knee joint) (toluidine blue-stained 0.5-μm-thick sections: ×100).Abbreviations: MPS IVA, mucopolysaccharidosis IVA; ERT, enzyme replacement therapy.Impact of enzyme replacement therapy and hematopoietic stem cell transplantation in patients with Morquio A syndrome. Tomatsu S, Sawamoto K, Alméciga-Díaz CJ, Shimada T, Bober MB, Chinen Y, Yabe H, Montaño AM, Giugliani R, Kubaski F, Yasuda E, Rodríguez-López A, Espejo-Mojica AJ, Sánchez OF, Mason RW, Barrera LA, Mackenzie WG, Orii T - Drug design, development and therapy (2015). Not Altered. CC.