Bowen disease of the penis is penile in situ squamous cell carcinoma.

What is the Pathology of Bowen Disease of The Penis?

The pathology of Bowen disease of the penis is: 

-Etiology: The cause of Bowen disease of the penis is may be related to uncircumcised, immunosuppression, balanitis, smoking, HPV 8 and 16, lichen planus. 

-Genes involved: Unknown. 

-Pathogenesis: The sequence of events that lead to Bowen disease of the penis trivial grazes on the prepuce or glans, progressively grow slowly edgewise along the surface, covering the full glans, and finally may invade the penile corpora and shaft. 

-Morphology: The morphology associated with Bowen disease of the penis shows red papules and plaques glans.

-Histology: The histology associated with Bowen disease of the penis shows parakeratosis, dyskeratosis, epidermal acanthosis, and epidermal atypia.

How does Bowen Disease of The Penis Present? 

Patients with Bowen disease of the penis typically males that present at an age range of 20-80 years. The symptoms, features, and clinical findings associated with Bowen disease of the penis include pain, scaling, dysuria, itching, ulceration, bleeding, red papules, and plaques.

How is Bowen Disease of The Penis Diagnosed? 

Bowen disease of the penis is diagnosed through biopsy and histological examination. 

How is Bowen Disease of The Penis Treated? 

Bowen disease of the penis is treated topical imiquimod of 5-fluorouracil. 

What is the Prognosis of Bowen Disease of The Penis?

The prognosis of Bowen disease of the penis is fair if acknowledged and managed early.