Cell death is the event of a biological cell ceasing to carry out its functions and it occurs when cultures become overcrowded. Morphologically, cell death can be classified into four different forms: apoptosis, autophagy, necrosis, and entosis. This may be the result of the natural process of old cells dying and being replaced by new ones, or of the disease, localized injury, and the death of the organism of which the cells are part.
WHAT IS CELL DEATH?
Effect of 5-FU on cell death morphology in esophageal cancer cell lines. Following 5-FU treatment (40 μ – 48 h), KYSE70 and KYSE450 cells display features of non-apoptotic cell death/type II cell death (arrowheads). OE21 cells display features of apoptosis (arrows) ( × 40 magnification). The BH3 mimetic HA14-1 enhances 5-fluorouracil-induced autophagy and type II cell death in esophageal cancer cells. Nyhan MJ, O'Donovan TR, Elzinga B, Crowley LC, O'Sullivan GC, McKenna SL - British journal of cancer (2012). Not Altered. CC.
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What is Apoptosis? 