(a) The images showed that H2O2 provokes cell aging, which is protected by dandelion extracts. The aging cells had higher gal activity and stained with blue color. HDFs were also incubated with DAPI for nucleus staining for cell counting. (b) was the statistical analysis from (a). HDFs were treated with H2O2 (100 μM) with or without dandelion extracts (300 μg/mL) for 72 hours. The percentage of aged cells was calculated from the number of blue-stained cells to the total cells counted. Dandelion Extracts Protect Human Skin Fibroblasts from UVB Damage and Cellular Senescence: Yang Y, Li S - Oxidative medicine and cellular longevity (2015). Not altered. CC.
Cellular aging also known as cellular senescence is when a cell has no longer ability to proliferate.