A) Representative image of I/R-induced autophagosome formation by electron microscopy, Scale bar = 2 µm, The areas in D3 from Wt and D14 from TerC and TerT KO mice are composed of the enlarged autophagosomes; B) Immunoblot of LC3 indicating I/R-induced conversion from LC3 I to II; C) Prolonged P62 expression in mice with telomerase deficiency after I/R. D) Semiquantitation of the LC3 II /I ratio and P62 expression. n=4. Telomerase deficiency delays renal recovery in mice after ischemia-reperfusion injury by impairing autophagy: Cheng H, Fan X, Lawson WE, Paueksakon P, Harris RC - Kidney international (2015). Not altered. CC.