What is Chronic Cervicitis?

Chronic Cervicitis
(a) Chronic cervicitis - Section shows normal squamous epithelial lining with sparse inflammatory infiltrate in the stroma (HPE [H and E, ×10, ×40]). (b) Negative immunostaining in a case of chronic cervicitis (p16INK4a [IHC, ×10, ×40). (c) Negative immunostaining in a case of chronic cervicitis (Ki-67 [IHC, ×10, ×40]). Role of p16/INK4a and Ki-67 as specific biomarkers for cervical intraepithelial neoplasia: An institutional study. Journal of Laboratory Physicians. Not Altered. CC.

Chronic cervicitis is an inflammation of the cervical tissue that has persisted despite attempts at treatment with various antibiotic regimens.

What is the Pathology of Chronic Cervicitis?

The pathology of chronic cervicitis is:

-Etiology: The cause of chronic cervicitis are allergy, irritation, pregnancy, cancer or treatment of cancer.

-Genes involved: 4977 bp deletion in mitochondrial genes.

-Pathogenesis: The sequence of events that lead to chronic cervicitis.

-Morphology: The morphology associated with chronic cervicitis shows pale uniform chromatin, lymphocytes of varying stages of maturation, scattered plasma cells.

-Histology: The histology associated with chronic cervicitis shows lymphoplasmacytic inflammation, ulceration, necrosis, and multinucleated cells.

How does Chronic Cervicitis Present?

Patients with chronic cervicitis typically females from young age to postmenopausal age. The symptoms, features, and clinical findings associated with chronic cervicitis include red and inflamed cervix, irritation, pelvic pain, purulent discharge, urinary problems, bleeding abnormally.

How is Chronic Cervicitis Diagnosed?

Chronic cervicitis is diagnosed by cervical biopsy, cervical discharge culture, physical examination, and pap smear. 

How is Chronic Cervicitis Treated?

Chronic cervicitis is treated by antibiotics for infections, surgery, and laser treatment.

What is the Prognosis of Chronic Cervicitis?

The prognosis of chronic cervicitis is good. It will go away a few days to a week after you start taking antibiotics or other treatments.