What is Delayed Hemolytic Transfusion Reaction?

Delayed Hemolytic Transfusion Reaction
Delayed Hemolytic Transfusion Reaction. Pre-transfusion a and post-transfusion b chest x-rays. Rare antibody-associated hemolytic transfusion reaction and transfusion-related acute lung injury: a case report. Beck TN, Young NG, Erickson ML, Prats I.BMC Surg (2017). Not Altered. CC.

Delayed hemolytic transfusion reaction is a type of reaction that occurs 2 to several months later after blood transfusion and is characterized by hemolysis.

What is the Pathology of Delayed Hemolytic Transfusion Reaction?

The pathology of delayed hemolytic transfusion reaction is:

-Etiology: The cause of delayed hemolytic transfusion reaction is development of antibodies to red blood cells antigens.

-Genes involved: None.

-Pathogenesis: The sequence of events that lead to delayed hemolytic transfusion reaction occurs later after transfusion due to the amnestic response if the immune system to a foreign red blood cell.

-Morphology: NA.

-Histology: NA.

How does Delayed Hemolytic Transfusion Reaction Present? 

Patients with delayed hemolytic transfusion reaction typically female present at age range of adulthood. The symptoms, features, and clinical findings associated with delayed hemolytic transfusion reaction include fever, mild jaundice, and drop in the Hb levels.

How is Delayed Hemolytic Transfusion Reaction Diagnosed? 

Delayed hemolytic transfusion reaction is diagnosed history taking, Hb levels, direct antiglobulin test. 

How is Delayed Hemolytic Transfusion Reaction Treated? 

Delayed hemolytic transfusion reaction is treated avoid red blood cells transfusion again, high dosage of steroids is recommended, pain medication.

What is the Prognosis of Delayed Hemolytic Transfusion Reaction?

The prognosis of delayed hemolytic transfusion reaction is fair if diagnosed and noted early.