What is Febrile Non-hemolytic Transfusion Reaction?

Febrile Non-hemolytic Transfusion Reaction
Febrile Non-hemolytic Transfusion Reaction. Representative histology. Representative haemotoxylin and eosin stained lung sections analysed histologically for pulmonary oedema. These range from no pulmonary oedema (A) through to mild (B), moderate (C) and severe (D) pulmonary oedema. Neutrophils were identified by morphological assessment and are indicated by the blue arrows (E and F). In contrast to sham sheep (E), there was widespread evidence of neutrophil infiltration in the lungs of LPS-stored sheep (F). LPS, lipopolysaccharide.Age of blood and recipient factors determine the severity of transfusion-related acute lung injury (TRALI). Tung JP, Fraser JF, Nataatmadja M, Colebourne KI, Barnett AG, Glenister KM, Zhou AY, Wood P, Silliman CC, Fung YL - Critical care (London, England) (2012). Not Altered. CC.

Febrile non-hemolytic transfusion reaction is a reaction that occurs as a result of antibodies attacking the white blood cells and is characterized by increased body temperature.

What is the Pathology of Febrile Non-Hemolytic Transfusion Reaction?

The pathology of febrile non-hemolytic transfusion reaction is:

-Etiology: The cause of febrile non-hemolytic transfusion reaction is the accumulation of cytokines in the blood.

-Genes involved: None.

-Pathogenesis: The sequence of events that lead to febrile non-hemolytic transfusion reaction during blood storage is the development of antibodies against the leukocytes. These antibodies fight the white blood cells, causing a reaction once transfusion is done.

-Morphology: NA.

-Histology: NA.

How does Febrile Non-Hemolytic Transfusion Reaction Present? 

Patients with febrile non-hemolytic transfusion reaction typically affect males and females present at an age range of childhood to adulthood. The symptoms, features, and clinical findings associated with include fever, chills, and malaise.

How is Febrile Non-Hemolytic Transfusion Reaction Diagnosed? 

Febrile non-hemolytic transfusion reaction is diagnosed physical examination, vital signs monitoring.

How is Febrile Non-Hemolytic Transfusion Reaction Treated? 

Febrile non-hemolytic transfusion reaction is treated by management of the symptoms which include antipyretics and leukocytes therapy, steroids and stopping the blood transfusion.

What is the Prognosis of Febrile Non-Hemolytic Transfusion Reaction?

The prognosis of febrile non-hemolytic transfusion traction is good.

Tags:
Last updated on May 22, 2022