Hemophilia A is an X-linked, recessive bleeding disorder.
What is the Pathology of Hemophilia A?
The pathology of hemophilia A is:
-Etiology: The cause of hemophilia A is an inherited or acquired genetic mutation that results in deficiency or dysfunction of factor VIII.
-Genes involved: X linked FVIII.
-Pathogenesis: The sequence of events that lead to hemophilia A is abnormal or absence of factor VIII clotting factor.
How does Hemophilia A Present?
Patients with hemophilia A typically are males that present with excessive bleeding at a young age. Other symptoms, features, and clinical findings associated with hemophilia A include easy bruising, hemarthrosis, and epistasis.
How is Hemophilia A Diagnosed?
Hemophilia A is diagnosed with medical history, and clotting factor tests.
How is Hemophilia A Treated?
Hemophilia A is treated with factor replacement as needed.
What is the Prognosis of Hemophilia A?
The prognosis of hemophilia A is fair.