Congo red stain excluded the presence of amyloid in the heart ((a)-(b)), while Masson's trichrome stain showed diffuse hypertrophy of myocytes and an interstitial fibrosis with the myocardium (blue areas (c), area of fibrosis of 7% by quantification analysis in (d)), indicating the presence of hypertensive heart disease. In addition, immunohistochemical stain for desmin and CD68 suggested the absence of myocardial texture disorders and macrophage infiltration ((e)-(f)).Severe Left Ventricular Hypertrophy, Small Pericardial Effusion, and Diffuse Late Gadolinium Enhancement by Cardiac Magnetic Resonance Suspecting Cardiac Amyloidosis: Endomyocardial Biopsy Reveals an Unexpected Diagnosis. Hofmann NP, Giusca S, Klingel K, Nunninger P, Korosoglou G - Case reports in cardiology (2016). Not Altered. CC.