What is Hypertrophic Cardiomyopathy?

Hypertrophic Cardiomyopathy
Transthoracic echocardiogram. A: Parasternal long axis view showing asymmetric septal hypertrophic cardiomyopathy in end diastole. B: A four-chamber view showing a combination of basal and mid-ventricular hypertrophic cardiomyopathy and an apical aneurysm (*). (LA = left atrium, RA = right atrium, RV = right ventricle, LV = left ventricle, Ao = aorta).Subaortic and mid-ventricular obstructive hypertrophic cardiomyopathy with an apical aneurysm: a case report. Cianciulli TF, Saccheri MC, Konopka IV, Serans DF, Acunzo RS, Escudero AM, Masoli OH, Prezioso HA - Cardiovascular ultrasound (2006). Not Altered. CC.

Hypertrophic cardiomyopathy is a genetic disease characterized by an increase in the left ventricular wall thickness. 

What is the Pathology of Hypertrophic Cardiomyopathy?

Hypertrophic cardiomyopathy pathology is due to mutation of cardiac sarcomere protein genes transmitted in an autosomal dominant trait. 

How does Hypertrophic Cardiomyopathy Present?

Hypertrophic cardiomyopathy presents as dyspnea, syncope, presyncope, angina, palpitations, orthopnea, paroxysmal nocturnal dyspnea, congestive heart failure, dizziness, and sudden cardiac death.

How is Hypertrophic Cardiomyopathy Diagnosed?

Hypertrophic cardiomyopathy diagnosis include 2D echo, routine laboratory tests and genetic testing. 

How is Hypertrophic Cardiomyopathy Treated?

Hypertrophic cardiomyopathy treatment includes beta blockers, calcium channel blockers, and antitussives. Surgery, alcohol ablation or pacing is also conducted. 

What is the Prognosis of Hypertrophic Cardiomyopathy?

Hypertrophic cardiomyopathy prognosis is good with an annual mortality of only <1%-6%.