What is Immune Complex-Associated Vasculitis?

Immune Complex-Associated Vasculitis
H/E stain of bone marrow, demonstrating histiocytes with hemophagocytosis (engulfing erythrocytes indicated by the arrow) and with CD-68 staining positive cells in the insert. Hemophagocytic lymphohistiocytosis in a patient with Goodpasture's syndrome: a rare clinical association: Basnet A, Cholankeril MR - The American journal of case reports (2014). Not altered. CC.

Immune complex-associated vasculitis is a disease that occurs as a result of the accumulation of the immune complexes in the blood vessels causing them to become inflamed it’s mostly seen in immunological disorders.

What is the Pathology of Immune Complex- Associated Vasculitis?

The pathology of immune complex-associated vasculitis is:

-Etiology: The cause of immune complex-associated vasculitis may be due to an infection, medication, autoimmune disorders, 

-Genes involved: Unknown.

-Pathogenesis: The sequence of events that lead to immune complex-associated vasculitis accumulates the immunoglobulins in the blood vessels.

-Morphology: NA.

-Histology: The histology associated with immune complex-associated vasculitis is the presence of infiltrating leucocytes and fibrinoid necrosis. 

How does Immune Complex-Associated Vasculitis Present? 

Patients with immune complex-associated vasculitis typically are males. The symptoms, features, and clinical findings associated with immune complex-associated vasculitis include palpable purpura which are cutaneous palpable lesions in the lower extremities, 

How is Immune Complex-Associated Vasculitis Diagnosed? 

Immune complex-associated vasculitis is diagnosed with x-rays, CT-scan, ultrasounds, and MRI.

How is Immune Complex-Associated Vasculitis Treated? 

Immune complex-associated vasculitis is treated through corticosteroids and immunosuppressors.

What is the Prognosis of Immune Complex-Associated Vasculitis?

The prognosis of immune complex-associated vasculitis is good since it has a low mortality rate and one can recover in months.