What is Inflammation of the Testis or Epididymis?

Inflammation of the Testis or Epididymis
Hematoxylin eosin (HE) staining showing the medium-sized artery in the testicular parenchyma showing fibrinoid necrosis and segmental involvement of moderate inflammatory cell infiltrate and perivascular inflammation (200x).Primary testicular necrotizing vasculitis clinically presented as neoplasm of the testicle: a case report. Maričić A, Stifter S, Valenčić M, Dorđević G, Markić D, Spanjol J, Sotošek S, Fučkar Z - World journal of surgical oncology (2011). Not Altered. CC.

Inflammation of the testis or epididymis is a medical condition characterized by pain, swelling, redness and hotness, and sometimes loss of function of the testis.

Examples of inflammation of the testis or epididymis includes:

  • Inflammation of the testis or epididymis due to gonorrhea
  • Inflammation of the testis or epididymis due to syphilis
  • Inflammation of the testis or epididymis due to mumps
  • Inflammation of the testis or epididymis due to tuberculosis
  • Autoimmune orchitis aka granulomatous orchitis
  • Nonspecific epididymitis
  • Nonspecific orchitis
Type of inflammation &CausePresentation DiagnosisTreatmentPrognosis
GonorrheaDevelopment of frank abscesses in the epididymis, resulting in extensive destruction of this organInflammation of the Testis or Epididymis diagnosed through medical history and examination. Laboratory studies-complete blood count, Imaging studies- scrotal ultrasonographyInflammation of the Testis or Epididymis treated through medical care treating underlying causes, Surgical incisionInflammation of the Testis or Epididymis prognosis is good with proper treatment of the underlying cause.
SyphilisThe morphologic pattern takes two forms: a diffuse interstitial inflammation branded by edema, and plasma cell and lymphocytic penetration with the typical hallmark of all syphilitic contagions   
MumpsInterstitial orchitis progresses 1 week after start of swelling to the parotid glands   
TuberculosisRaises the classic morphological responses of caseating granulomatous inflammation that are distinctive of tuberculosis illness.   
Autoimmune Orchitis aka Granulomatous OrchitisA painless testicular mass imitating a testicular tumor. Histologically, the orchitis is illustrious by granulomas seen confined in spermatic tubules.   
Nonspecific Epididymitis & Nonspecific Orchitis caused by sexually transmitted pathogens Chlamydia trachomatis and Neisseria gonorrhoeaeInfection limited to the interstitial connective tissue, extends involving the tubules and progress to free abscess formation or whole suppurative necrosis of the epididymis. The infection extends into the testis