What is Jaundice?

Jaundice
Immunostaining of DCP and NX-DCP in liver tissue of a patient with obstructive jaundice. (A-C) Liver tissue in a case of obstructive jaundice showing NX-DCP expression, but no DCP expression. HE stain (A), and immunostain for DCP (B) and NX-DCP (C). (D-F) Biliary epithelial cells of the same case showing NX-DCP expression, but no DCP expression. HE stain (D), and immunostain for DCP (E) and NX-DCP (F). Des-γ-carboxyprothrombin (DCP) and NX-DCP expressions and their relationship with clinicopathological features in hepatocellular carcinoma: Sumi A, Akiba J, Ogasawara S, Nakayama M, Nomura Y, Yasumoto M, Sanada S, Nakashima O, Abe T, Yano H - PloS one (2015). Not altered. CC.

Jaundice is the condition in which the skin, whites of the eyes, and mucous membranes turn yellow because of a high level of bilirubin.

Causes of jaundice include: 

  • Bile duct obstruction
  • Neonatal cholestasis 
  • Biliary atresia
  • Primary hepatolithiasis