A – Red pulp congestion (HE, 100X); B – Detail of the red pulp with acute splenitis (HE, 400X); C – Photomicrography of the kidney showing a scar due to pyelonephritis with basophilic calcification (HE, 100X); D – Renal cortical parenchyma with acute tubular necrosis (HE, 100X). Lemierre's syndrome due to intratumoral abscess of the uvula: Rahhal H, de Campos FP, Ferreira CR, Felipe-Silva A - Autopsy & case reports (2015). Not altered. CC.
Nonspecific acute splenitis is inflammation of the spleen that is often accompanied by enlargement. The inflammation may be due to micro-organisms or the immune modulators such as cytokines that are released as a response.