What is Oncocytoma?

Oncocytoma
Oncocytoma. Representative images of the oncocytomas included in this study. A, Axial contrast-enhanced CT, axial SPECT (B), and axial SPECT/CT fusion images of a right upper pole oncocytoma (C) with a representative histologic image (D, hematoxylin and eosin stain [HE] ×20) (patient 1, white and black arrowheads). E, Axial contrast-enhanced T1-weighted MRI, axial SPECT (F), and axial SPECT/CT fusion images of a right medial interpolar oncocytoma (G) with an accompanying histologic image (H, HE ×20) (patient 2, white and black arrowheads). I, Coronal contrast-enhanced CT, coronal SPECT (J), and coronal SPECT/CT fusion images of a right lower pole oncocytoma (K) with a corresponding histologic image (L, HE ×20) (patient 3, white and black arrowheads). Initial experience using 99mTc-MIBI SPECT/CT for the differentiation of oncocytoma from renal cell carcinoma. Rowe SP, Gorin MA, Gordetsky J, Ball MW, Pierorazio PM, Higuchi T, Epstein JI, Allaf ME, Javadi MS - Clinical nuclear medicine (2015). Not Altered. CC.

Oncocytoma is a rare salivary gland tumor consisting of oncocytes with many mitochondria.

What is the Pathology of Oncocytoma?

The pathology of oncocytoma is: 

-Etiology: The cause of oncocytoma is related to viral insult. 

-Pathogenesis: The sequence of events that lead to oncocytoma is not known. 

-Histology: The histology associated with oncocytoma is benign epithelial tumors with oncocytes with eosinophilic granular cytoplasm that contain many mitochondria. 

How does Oncocytoma Present?

Patients with oncocytoma typically are slightly predominant in female gender, present at age range of most commonly from the sixth to eighth decades. The symptoms, features, and clinical findings associated with oncocytoma include a lobulated, mobile mass. 

How is Oncocytoma Diagnosed?

Oncocytoma is diagnosed by imaging, fine needle aspiration, and biopsy. 

How is Oncocytoma Treated?

Oncocytoma is treated by complete surgical excision. 

What is the Prognosis of Oncocytoma?

The prognosis of oncocytoma is fair.