What is Phlebothrombosis?

Phlebothrombosis
Phlebothrombosis. (A–C) Grade I main PVT (white arrows), Grade IV mesenteric vein (black arrows) and lateral branches (hollow arrows). (D) Grade I main PVT after TIPS (white arrows) with the shunt (white star). (E) One month after TIPS, the mesenteric vein thrombosis disappeared (black star). Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis. Scientific Reports. Not altered. CC.

Phlebothrombosis is a clot occurrence within a vein, which is not related to the venous wall inflammation.

What is the Pathology of Phlebothrombosis?

The pathology of phlebothrombosis is:

-Etiology: The cause of phlebothrombosis is inactivity, malignancy, use of oestrogen-containing compounds, cardiac failure, and postoperative state.

-Genes involved: None.

-Pathogenesis: The sequence of events that lead to phlebothrombosis results from initiated triad of changes: endothelial injury, change in the composition of blood and venous stasis.

-Morphology: The morphology associated with phlebothrombosis shows affected area firm and distended.

-Histology: The histology associated with phlebothrombosis shows thick-walled fibrous vein.

How does Phlebothrombosis Present? 

Patients with phlebothrombosis are typically females in there forties or above. The symptoms, features, and clinical findings associated with phlebothrombosis include distal edema, superficial vein dilation, heat, tenderness, redness, swelling, pain, and cyanosis.

How is Phlebothrombosis Diagnosed? 

Phlebothrombosis is diagnosed through clinical presentations. Imaging such as venous duplex ultrasonography may be helpful.

How is Phlebothrombosis Treated? 

Phlebothrombosis is treated through limited activity of the affected part, moist heat application. Medical therapy- anticoagulants and antibiotics.

What is the Prognosis of Phlebothrombosis?

The prognosis of phlebothrombosis is good in case of local effect of the condition and worse in case of systemic effects.