Primary chronic adrenocortical insufficiency is characterized by a chronic decreased aldosterone and cortisol production due to diminished gland function.
Examples of primary chronic adrenocortical insufficiency include:
- Addison disease
- Autoimmune adrenalitis
- Autoimmune polyendocrine syndrome type 1 (APS1)
- Autoimmune polyendocrine syndrome type 2 (APS2)
- Tuberculosis adrenalitis
- Infections related adrenocortical insufficiency
- Metastasis related adrenocortical insufficiency
- Genetic related adrenocortical insufficiency