Sebaceous carcinoma is a rare malignant tumor of the skin mostly common to the eyelid.

What is the Pathology of Sebaceous Carcinoma? 

The pathology of sebaceous carcinoma arises from the adnexal epithelium of sebaceous glands commonly the meibomian glands or glands of Zeis.

How does Sebaceous Carcinoma Present?

Sebaceous carcinoma presents with yellow, hard, painless subcutaneous nodule, red and yellow or red and brown ulcerated papules, may also appear as nonmelanoma skin cancer.

How is Sebaceous Carcinoma Diagnosed?

Sebaceous carcinoma is diagnosed by conjunctiva biopsy, and sentinel lymph node biopsy.

How is Sebaceous Carcinoma Treated?

Sebaceous carcinoma is treated with targeted therapy as (retinoid receptor ligands, anti-androgen), chemotherapy, immunotherapy, Mohs micrographic surgery, and wide local excision. 

What is the Prognosis of Sebaceous Carcinoma?

The prognosis of sebaceous carcinoma is fair.