What is Sexual Dysfunction Related to Pituitary Gland Disorder?

Sexual Dysfunction Related to Pituitary Gland Disorder
53-year old man with right sided claudication and erectile dysfunction.A. Anteroposterior diagnostic pelvic angiography shows right external iliac artery occlusion and hypertrophied right internal iliac artery. Distal abdominal aorta was mildly aneurysmatic (3.6 cm in diameter). B. Left oblique diagnostic angiography shows right external iliac artery occlusion, hypertrophied right internal iliac artery, and collateral flow via dilated obturator (thick arrow) and medial femoral circumflex arteries (thin arrows) to right common femoral artery. C. Right oblique diagnostic angiography shows normal left main, internal, and external iliac arteries. D. After percutaneous transluminal angioplasty and stenting, angiogram shows normal calibration and excellent patency of right external iliac artery. Flow through right internal iliac artery slowed immediately, as a result of decrased volume. Right medial femoral circumflex artery was not seen on angiogram. E. Late phase of post-stent arteriography shows internal iliac artery branches better.Impotence due to external iliac steal syndrome: treatment with percutaneous transluminal angioplasty and stent placement. Gür S, Oguzkurt L, Kaya B, Tekbas G, Ozkan U - Korean journal of radiology (2012). Not Altered. CC.

Sexual dysfunction related to pituitary gland disorder is sexual hyperfunction and/or hypofunction linked to the diseased pituitary gland in males and females

The pathology of sexual dysfunction related to pituitary gland disorder is: 

-Etiology: The cause of sexual dysfunction related to pituitary gland disorder is tumors to the pituitary gland, conditions such as hypopituitarism, medication such as dopamine agonist.

-Genes involved: Unknown.

-Pathogenesis: The sequence of events that lead to sexual dysfunction related to pituitary gland disorder same as that of hypopituitarism, resulting from incapability of the hypothalamic LHRH pulse creator and/or incapability to pituitary responding with LH and FSH secretion. Interruption of the hypothalamic-pituitary-gonadal axis. Gonad does not produce sex steroids adequate to overpower the secretion of LH and FSH.

-Morphology: Gonadal abnormalities.

-Histology: Decreased spermatogenesis. Decreased ovulation.

Patients with sexual dysfunction related to pituitary gland disorder typically affect more females than males present at an age range of 20 to 45 years. The symptoms, features, and clinical findings associated with sexual dysfunction related to pituitary gland disorder.

Sexual dysfunction related to pituitary gland disorder is diagnosed through laboratory studies, such as FSH levels, LH levels, TFTs, prolactin levels, semen analysis, and ACTH stimulation test.

Sexual dysfunction related to pituitary gland disorder is treated through supportive therapy, hormonal replacement therapy, tapering down dopamine agonists in the treatment of hypopituitarism.

The prognosis of sexual dysfunction related to pituitary gland disorder is good.