Central nervous system white matter lesions. 45-year-old male. T2 Brain MR image showed widespread, punctuated and confluent white matter lesions from periventricular to subcortical spaces. These lesions are associated with severe axonal injury (gliosis).Fibrosis: a key feature of Fabry disease with potential therapeutic implications.
Weidemann F, Sanchez-Niño MD, Politei J, Oliveira JP, Wanner C, Warnock DG, Ortiz A - Orphanet journal of rare diseases (2013). Not Altered. CC.
Trauma of the central nervous system is injury to the brain or spinal cord. This is known as traumatic brain injury (TBI) and spinal cord injury (SCI). Trauma pushes the activation of the nervous system beyond its ability to self-regulate.