What is Uniparental Disomy?

Uniparental Disomy
Facial appearance of patients with maternal uniparental disomy of chromosome 7 with increasing age. Group A: 1.3–3.8 years; group B: 4.0–7.9 years; group C: 10.0–14.2 years. Epigenotype-phenotype correlations in Silver-Russell syndrome. Wakeling EL, Amero SA, Alders M, Bliek J, Forsythe E, Kumar S, Lim DH, MacDonald F, Mackay DJ, Maher ER, Moore GE, Poole RL, Price SM, Tangeraas T, Turner CL, Van Haelst MM, Willoughby C, Temple IK, Cobben JM - Journal of medical genetics (2010). Not Altered. CC.

Uniparental disomy occurs when both homologous chromosomes are inherited from one parent.