Representative photomicrographs of immunohistochemistry of TLR2 in the right atrial appendages.Gradually decreased levels of TLR2 (stained brown only in the cytoplasm) were observed in PaAF (A), PeAF (B), and SR(C) patients with valvular heart disease (original magnification, ×200).TLR2 was overexpressed independent of IL-6 in patients with valvular atrial fibrillation. Wang J, Xue L, Cao H, Cui F, Dai T, Chen Y - Journal of biomedical research (2011). Not Altered. CC.