Representative formalin-fixed paraffin embedded autopsy brain frontal lobe tissue from HIV- (a-d) and HIV+ (e-h) cases stained with hematoxylin and eosin (a-c, e-g) or luxol fast blue and periodic acid-Schiff (d, h). A minority of HIV+ and HIV- cases were histologically unremarkable (a, e). Many HIV+ and HIV- cases exhibited mild histopathologic abnormalities including hypercellular white matter (b, f), increased rod cells (microglia) (c, g), and/or moderately thickened blood vessels (d, h). Original magnification 200× (a-b, e-f), 400× (d, h), and 1000× (c, g). Brain and liver pathology, amyloid deposition, and interferon responses among older HIV-positive patients in the late HAART era: BMC Infectious Diseases. Not altered. CC.