Pick Disease

Demyelinating Disorders Pathology Study Guide

Demyelinating Disorders Demyelinating disorders are pathologic conditions due to the degeneration of myelin. Axons are insulated by myelin, which increases conduction efficiency and speed. Oligodendrocytes myelinate the central nervous system. Schwann cells myelinate the peripheral nervous system. Myelin and oligodendrocytes…
Neurodegenerative Disorders

Neurodegenerative Disorders Pathology Study Guide

Neurodegenerative Disorders Neurodegenerative disorders are degenerative conditions that effect the central nervous system (CNS). In this section we present the following neurodegenerative conditions: Dementia Alzheimer disease Vascular dementia Pick disease Parkinson disease Huntington disease Normal pressure hydrocephalus Spongiform encephalopathy Dementia…
Osteosarcoma

Bone Pathology Study Guide

Bone Pathology Achondroplasia Achondroplasia literally means without chondrocyte growth. A-chondro-plasia. Achondroplasia is characterized by decreased cartilage proliferation in the development plate. Achondroplasia is the most common cause of dwarfism. Achondroplasia is related to an autosomal dominant (AD) activating mutation in…
Pneumothorax

Pleura Pathology Study Guide

Pleura pathology involves abnormalities of the pleura. Pleura pathology includes: Pneumothorax Mesothelioma Pneumothorax Pneumothorax is air buildup in the pleural space. Spontaneous pneumothorax is because of rupture of an emphysematous bleb. Pneumothorax leads to collapse of a portion of the…
MUSCLE PATHOLOGY

Skeletal Muscle Pathology Study Guide

Skeletal muscle pathology is the study of diseases and disorders that effect skeletal muscle. In this section we highlight non neoplastic entities that effect skeletal muscle, which include: Dermatomyositis Polymyositis Muscular dystrophy (Duchenne muscular dystrophy & Becker muscular dystrophy) Neuromuscular…
SALIVARY GLAND PATHOLOGY

Salivary Gland Pathology Study Guide

Salivary Gland Pathology Saliva is produced by exocrine salivary glands, which are found inside the mouth. There are three pairs of salivary glands, one pair in each of the tongue, lips, and cheeks beneath the skin. Each gland consists of…
Steven-Johnson-Syndrome

Skin Pathology Study Guide

Skin The skin serves as a defense against fluid loss and environmental irritants. Skin is made up of a dermis and an epidermis. The epidermis is composed of keratinocytes and has five layers: Basale Spinosum Granulosum Lucidum Corneum The regenerative…
Gout monosodium urate crystals in joint fluid

Joint Pathology Study Guide

Joint pathology is the study of diseases and disorders that effect the joints. In this section we will focus on the following joint pathology: Osteoarthritis Rheumatoid arthritis Seronegative spondyloarthropathies (ankylosing spondylitis, Reiter syndrome, psoriatic arthritis) Infectious arthritis Gout Pseudogout Joint…
Lipoma

Soft Tissue Tumors Pathology Study Guide

Lipoma A lipoma is a benign tumor composed of adipose tissue that typically develops just beneath the skin.  Lipomas are most commonly seen in adults. Lipomas may be treated by surgical excision. Definitive diagnosis of lipoma is made by pathology…
Infections of the Oral Cavity

Oral Cavity Pathology Study Guide

Oral cavity pathology includes: Cleft lip Cleft palate Aphthous ulcer Behçet syndrome Oral herpes Squamous cell carcinoma Leukoplakia Oral candidiasis Hairy leukoplakia Erythroplakia Cleft Lip The five facial prominences grow and usually unite to create the face during the early…