AIDS

What is AIDS?

AIDS is acquired immunodeficiency syndrome. AIDS is a chronic, potentially life-threatening condition caused by the human immunodeficiency virus (HIV). HIV interferes with the ability to fight infections.  What is the Pathology of AIDS?  The pathology of AIDS is:   -Etiology: The…
Secondary Immunodeficiencies

What are Secondary Immunodeficiencies?

Secondary immunodeficiencies are the result of disease or other environmental factors weakening the immune system. A prime examples of a secondary immunodeficiency disorder is acquired immunodeficiency syndrome (AIDS). 
Ataxia-Telangiectasia

What is Ataxia Telangiectasia?

Ataxia telangiectasia is a rare inherited disorder that affects the nervous system, immune system, and other body systems. This disorder is characterized by progressive difficulty with coordinating movements.    What is the Pathology of Ataxia Telangiectasia?  The pathology of ataxia telangiectasia…
Wiskott-Aldrich Syndrome

What is Wiskott-Aldrich Syndrome?

Wiskott–Aldrich syndrome is a rare X-linked recessive disease characterized by eczema, thrombocytopenia (low platelet count), immune deficiency, and bloody diarrhea. What is the Pathology of Wiskott–Aldrich Syndrome?  The pathology of Wiskott-Aldrich syndrome is:   -Etiology:  The cause of Wiskott-Aldrich syndrome is…
Severe Combined Immunodeficiency

What is Severe Combined Immunodeficiency?

Severe combined immunodeficiency is an inherited primary immunodeficiency disease that typically presents in infancy results in profound immune deficiency condition resulting in a weak immune system that is unable to fight off even mild infections. What is the Pathology of…
Thymic Hypoplasia

What is Thymic Hypoplasia?

Thymic hypoplasia results in aberrant T-cell production, which negatively effects immune respnse. Thymic hypoplasia is also knowns as DiGeorge  syndrome.   What is the Pathology of Thymic Hypoplasia?  The pathology of thymic hypoplasia aka DiGeorge  syndrome is:   -Etiology: The cause of…
Hyper-IgM Syndrome

What is Hyper-IgM Syndrome?

Hyper-IgM syndrome is an immunoglobulin deficiency syndrome that is characterized by normal or elevated serum IgM levels and decreased levels or absence of other serum immunoglobulins. Hyper-IgM syndrome can result in susceptibility to bacterial infections.    What is the Pathology of…
IgA Deficiency

What is IgA Deficiency?

IgA deficiency is a disease is of low or absent immunoglobulin A (IgA). IgA is normally found in mucous membranes, mainly in the respiratory and digestive tracts. IgA is also normally found in saliva, tears, and breastmilk. A deficiency of…
Common Variable Immunodeficiency

What is Common Variable Immunodeficiency?

Common variable immunodeficiency (CVID) is an immune system disorder that causes to have low levels of the proteins that help fight infections. Patients with common variable immunodeficiency (CVID) are likely to have repeated infections in ears, sinuses and respiratory system.  …
X-linked Agammaglobulinemia aka Bruton Agammaglobulinemia

What is X-linked Agammaglobulinemia aka Bruton Agammaglobulinemia?

Agammaglobulinemia aka Bruton agammaglobulinemia is an inherited (genetic) immune system disorder that reduces your ability to fight infections. Agammaglobulinemia is caused by a genetic mutation in a gene called Bruton’s tyrosine kinase.    What is the Pathology of X-linked Agammaglobulinemia?  The…