Burkitt Lymphoma

What is Burkitt Lymphoma?

Burkitt lymphoma is a highly aggressive non-hodgkin B cell lymphoma. They may occur in 3 categories: 1) African (endemic) Burkitt lymphoma, 2) sporadic (nonendemic) Burkitt lymphoma, and 3) a subset of aggressive lymphomas occurring in individuals infected with HIV. What…
Diffuse Large B-Cell Lymphoma

What is Diffuse Large B-Cell Lymphoma?

Diffuse large B-cell lymphoma is a neoplasm of large B lymphoid cells with nuclei at least twice the size of a lymphocyte.  What is the Pathology of Diffuse Large B-Cell Lymphoma? The pathology of diffuse large B-cell lymphoma is: -Etiology:…
Hairy Cell Leukemia

What is Hairy Cell Leukemia?

Hairy cell leukemia is a rare indolent lymphoproliferative neoplasm of mature B cells. What is the Pathology of Hairy Cell Leukemia? The pathology of hairy cell leukemia is: -Etiology: The cause of hairy cell leukemia is associated with point mutations…
Splenic Marginal Zone Lymphoma

What is Marginal Zone Lymphoma? 

Marginal zone lymphoma is a slow-growing type of B-cell non-Hodgkin lymphoma that begins forming in certain areas (marginal zones) of lymph tissue.  There are three types of marginal zone lymphomas: the extranodal MZL (EMZL) of mucosa-associated lymphoid tissue (MALT or…
Follicular Lymphoma

What is Follicular Lymphoma?

Follicular lymphoma is the most common form of indolent non-hodgkin lymphoma in the United States affecting 15,000 to 20,000 individuals per year. What is the Pathology of Follicular Lymphoma? The pathology of follicular lymphoma  is: -Etiology: The cause of follicular…
Mantle Cell Lymphoma FISH

What is Mantle Cell Lymphoma?

Mantle cell lymphoma is a lymphoproliferative disorder derived from a subset of naive pregerminal center cells localized in primary follicles or in the mantle region of secondary follicles. What is the Pathology of Mantle Cell Lymphoma? The pathology of mantle…
Extranodal Marginal Zone Lymphoma

What is Extranodal Marginal Zone Lymphoma?

Extranodal marginal zone lymphoma is a low-grade B-cell lymphoma that originate at virtually any extranodal site and arises in organs that normally lack lymphoid tissue (eg. stomach, intestine, thyroid, lung, and skin). What is the Pathology of Extranodal Marginal Zone…
Nodal Marginal Zone Lymphoma

What is Nodal Marginal Zone Lymphoma?

Nodal marginal zone lymphoma is a primary lymph node disease with morphologic and immunophenotypic features similar to those of splenic marginal zone lymphoma and extranodal marginal zone lymphoma.  What is the Pathology of Nodal Marginal Zone Lymphoma?  The pathology of…
Splenic Marginal Zone Lymphoma

What is Splenic Marginal Zone Lymphoma?

Splenic marginal zone lymphoma is a low-grade B-cell lymphoma that is unique to the spleen but that often secondarily involves the splenic hilar lymph nodes and usually involves the blood and bone marrow.  What is the Pathology of Splenic Marginal…
Lymphoplasmacytic Lymphoma

What is Lymphoplasmacytic Lymphoma?

Lymphoplasmacytic lymphoma is also known as Waldenstrom macroglobulinemia. It is a low-grade (slow-growing) B- cell lymphoproliferative neoplasm characterized by small lymphocytes and IgM monoclonal gammopathy.  What is the Pathology of Lymphoplasmacytic Lymphoma? The pathology of lymphoplasmacytic lymphoma is: -Etiology: The…