Limbic Encephalitis

What is Limbic Encephalitis?

Limbic encephalitis is a form of autoimmune encephalitis that is characterized by inflammation of the brain.  What is the Pathology of Limbic Encephalitis? Etiology: The cause of limbic encephalitis with an autoimmune reaction.  Pathogenesis: The pathological changes of paraneoplastic limbic…
Subacute Cerebellar Degeneration

What is Subacute Cerebellar Degeneration?

Subacute cerebellar degeneration is characterized by the deterioration of the area of the brain concerned with muscle coordination and balance.  There are two types of subacute cerebellar degeneration:  Paraneoplastic cerebellar degeneration due to cancerThiamine deficiency associated cerebellar degeneration, caused by…
Lambert-Eaton Myasthenic Syndrome

What is Lambert-Eaton Myasthenic Syndrome?

Lambert-Eaton myasthenic syndrome is a rare autoimmune disorder of the neuromuscular junction.  What is the Pathology of Lambert-Eaton Myasthenic Syndrome?  Etiology: The cause of Lambert-Eaton myasthenic syndrome is often a certain type of cancer called small cell lung cancer.  Pathogenesis:…
Eye Movement Disorders.

What are Eye Movement Disorders?

Eye movement disorders are prominent features of a range of paraneoplastic syndromes, especially those involving the brainstem and cerebellum. What is the Pathology of Eye Movement Disorders? Etiology: The cause of Eye movement disorders is from immune mechanisms of the…
Turcot Syndrome

What is Turcot Syndrome?

Turcot syndrome is a rare inherited disorder characterized by the association of benign growths (adenomatous polyps) in the mucous lining of the gastrointestinal tract with tumors of the central nervous system. What is the Pathology of Turcot Syndrome? Etiology: The…
Li-Fraumeni Syndrome

What is Li-Fraumeni Syndrome?

Li-Fraumeni syndrome is an inherited familial predisposition to a wide range of certain, often rare, cancers. This is due to a change (mutation) in a tumor suppressor gene known as TP53. The resulting p53 protein produced by the gene is…
Gorlin Syndrome

What is Gorlin Syndrome?

Gorlin syndrome is also known as nevoid basal cell carcinoma syndrome. Gorlin syndrome is a condition that affects many areas of the body and increases the risk of developing various cancerous and noncancerous tumors. What is the Pathology of Gorlin…
Neurofibromatosis

What is Neurofibromatosis?

Neurofibromatosis is a group of genetic disorders that cause tumors to form on nerve tissue. What is the Pathology of Neurofibromatosis?  Etiology: The cause of Neurofibromatosis is a family history of the disorder.  Genes involved: NF1 and NF2. Pathogenesis: The…