Amyotrophic lateral sclerosis is a progressive nervous system disease that affects nerve cells in the brain and spinal cord, causing loss of muscle control. ALS is also known as Lou Gehrig’s disease, after the baseball player who was diagnosed with…
Spinocerebellar degenerations are a group of hereditary ataxias that are characterized by degenerative changes in the cerebellum, and sometimes in the spinal cord. What is the Pathology of Spinocerebellar Degenerations? Etiology: The cause of Spinocerebellar degenerations may be genetics. Genes…
Huntington disease is a rare, inherited disease that causes the progressive breakdown of nervous cells in the brain. This disease causes changes in the central area of the brain, which affect movement, mood and thinking skills. What is the Pathology…
Multiple system atrophy is a progressive neurodegenerative disorder with a combination of symptoms that affect both the autonomic nervous system and movement. What is the Pathology of Multiple System Atrophy? Etiology: The cause of Multiple System Atrophy is unknown. Multiple…
Corticobasal degeneration is a progressive neurological disorder characterized by nerve cell loss and atrophy of multiple areas of the brain including the cerebral cortex and the basal ganglia. What is the Pathology of Corticobasal Degeneration? Etiology: The exact, underlying cause…
Progressive supranuclear palsy is a rare brain disorder that causes problems with movement, walking and balance, and eye movement. Progressive supranuclear palsy results from damage to nerve cells in the brain that control thinking and body movement. What is the…
Atypical parkinsonism syndromes are progressive diseases that present with some of the signs and symptoms of Parkinson disease, but do not respond well to drug treatment with levodopa. Aytpical parkinsonism syndromes are associated with abnormal protein buildup within brain cells.…
Parkinson disease is a neurodegenerative disorder that affects predominately dopaminergic neurons in the substantia nigra. What is the Pathology of Parkinson Disease? Etiology: The cause of Parkinson disease the loss of nerve cells in the substantia nigra. Genes involved: Parkin,…
Frontotemporal degeneration is a group of disorders that occur when nerve cells in the frontal and temporal lobes of the brain are lost. What is the Pathology of Frontotemporal Degeneration? Etiology: The cause of Frontotemporal degeneration is unknown. Genes involved:…