Gerstman-Straussler-Scheinker Syndrome

What is Gerstman-Straussler-Scheinker Syndrome?

Gerstman-Straussler-Scheinker syndrome is an extremely rare, usually familial inherited fatal neurodegenerative disease.  What is the Pathology of Gerstman-Straussler-Scheinker Syndrome? Etiology: The cause of Gerstman-Straussler-Scheinker Syndrome are the prions, which are a class of pathogenic proteins that are resistant to proteases.…
Kuru

What is Kuru?

Kuru is a rare, incurable and fatal neurodegenerative disorder caused by the transmission of abnormally folded proteins called prions. What is the Pathology of Kuru? Etiology: Kuru is an acquired infectious disease linked cannibalism.  Pathogenesis: A chain reaction of misfolded…
Creutzfeldt-Jakob disease

What is Creutzfeldt-Jakob Disease?

Creutzfeldt-Jakob disease is a transmissible spongiform encephalopathy that results in rapidly progressive dementia and death usually within a year from onset. The vast majority are sporadic, but familial and acquired forms are occasionally encountered. What is the Pathology of Creutzfeldt-Jakob…
Prion Diseases

What are Prion Diseases?

Prion diseases are or transmissible spongiform encephalopathies that can cause rare progressive neurodegenerative disorders that affect both humans and animals. Prion diseases are usually rapidly progressive and fatal. Examples of prion diseases include:  Creutzfeldt-Jakob diseasesKuruGerstman-Straussler-Scheinker syndromeFatal familial insomnia
Cerebrovascular Disease

What is Cerebrovascular Disease?

Cerebrovascular disease refers to a group of conditions that affect blood flow and the blood vessels in the brain. Problems with blood flow may occur from blood vessels narrowing (stenosis), clot formation (thrombosis), artery blockage (embolism), or blood vessel rupture…
Trauma of the Central Nervous System

What is Trauma of the Central Nervous System?

Trauma of the central nervous system is injury to the brain or spinal cord. This is known as traumatic brain injury (TBI) and spinal cord injury (SCI). Trauma pushes the activation of the nervous system beyond its ability to self-regulate. 
Cerebral Palsy

What is Cerebral Palsy?

Cerebral palsy is a group of disorders that affect a person’s ability to move and maintain balance and posture. Cerebral palsy is the most common motor disability in childhood.  What is the Pathology of Cerebral Palsy?  Etiology: The causes of…
Hydromyelia

What is Hydromyelia?

Hydromyelia is dilatation of the central canal of the spinal cord.  What is the Pathology of Hydromyelia? Etiology: The causes of hydromyelia includes infections, spinal tumors, and trauma.  Pathogenesis: The sequence of events that lead to hydromyelia is due to…
Syringomyelia

What are Syringomyelia?

Syringomyelia is the development of a fluid-filled cyst (syrinx) within the spinal cord. Over time, the cyst can enlarge and destroy the spinal cord. What is the Pathology of Syringomyelia?  Etiology: The causes of syringomyelia may include Chiari malformation, infections,…