How do Metastatic Tumors Affect Bone

How do Metastatic Tumors Affect Bone?

Metastatic tumors are the most common types of malignancies that affect the bones. Cancer that originates in one area of the body, such as an organ, gland, or tissue, and then spreads to the bone is called metastatic bone disease.…
Nonossifying Fibromas

What are Nonossifying Fibromas?

Nonossifying fibromas are benign fibrohistiocytic tumors arising in the metaphysis of long bones of skeletally immature individuals, composed of bland fibroblastic proliferation mixed with osteoclast-like giant cells.  What is the Pathology of Nonossifying Fibromas? The pathology of nonossifying fibromas is:…
Fibrous Dysplasias

What are Fibrous Dysplasias?

Fibrous dysplasia is a disorder where normal bone and marrow are replaced with fibrous tissue, resulting in the formation of bone that is weak and prone to expansion.  What is the Pathology of Fibrous Dysplasias? The pathology of fibrous dysplasias…
Fibrous Cortical Defects

What are Fibrous Cortical Defects?

Fibrous cortical defects are benign bony lesions and are a type of fibroxanthoma, histologically identical to the larger non-ossifying fibroma (NOF). What is the Pathology of Fibrous Cortical Defects? The pathology of fibrous cortical defects is: -Etiology: The cause of…
Giant Cell Tumor

What is Giant Cell Tumor?

Giant cell tumors are benign, aggressive tumors typically found in the epiphysis of long bones, most commonly at the distal femur and proximal tibia.  What is the Pathology of a Giant Cell Tumor? The pathology of a giant cell tumor…
Ewing Sarcoma

What is Ewing Sarcoma?

Ewing sarcoma is a malignant, distinctive small round cell sarcoma associated with a t(11:22) translocation and most commonly occurs in the diaphysis of long bones.  What is the Pathology of Ewing Sarcoma? The pathology of Ewing sarcoma is: -Etiology: The…
Tumors of Bone or Cartilage of Unknown Origin

What are Tumors of Bone or Cartilage of Unknown Origin?

Tumors of bone or cartilage of unknown origin are those tumors that originate elsewhere in the body with their location unknown but finally invade bone. Examples of bone or cartilage of unknown origin include:  Aneurysmal bone cystEwing sarcoma family tumorsGiant…