Pyogenic Osteomyelitis

What is Pyogenic Osteomyelitis?

Pyogenic osteomyelitis is an inflammation of the bone caused by an infecting organism.  What is the Pathology of Pyogenic Osteomyelitis? The pathology of pyogenic osteomyelitis is: -Etiology: The cause of pyogenic osteomyelitis is Staphylococcus aureus.  -Genes involved: None.  -Pathogenesis: The…
Osteomyelitis

What is Osteomyelitis?

Osteomyelitis is a serious infection of the bone that can be either acute or chronic. It is an inflammatory process involving the bone and its structures caused by pyogenic organisms that spread through the bloodstream, fractures, or surgery. Types of…
Osteonecrosis

What is Osteonecrosis?

Osteonecrosis is a degenerative bone condition characterized by the death of cellular components of the bone secondary to an interruption of the subchondral blood supply.  What is the Pathology of Osteonecrosis? The pathology of osteonecrosis is: -Etiology: The causes of…
Bone Fractures

What are Bone Fractures?

Bone fractures are a medical condition in which there is a partial or complete break in the continuity of a bone.  Types of fractures include: Simple fracturesCompound fracturesDisplaced fracturesStress fracturesGreenstick fracturesPathologic fractures What are Simple Fractures? Simple fractures are those…
Renal Osteodystrophy

What is Renal Osteodystrophy?

Renal osteodystrophy is a broad term that incorporates all the biochemical abnormalities and skeletal manifestations in patients suffering from chronic kidney disease or end-stage renal disease.  What is the Pathology of Renal Osteodystrophy? The pathology of renal osteodystrophy is: -Etiology:…
Hyperparathyroidism

What is Hyperparathyroidism?

Hyperparathyroidism is an increase in parathyroid hormone levels in the blood. What is the Pathology of Hyperparathyroidism? The pathology of hyperparathyroidism is: -Etiology: The cause of hyperparathyroidism is increased parathyroid or parathyroid like hormones.   -Genes involved: MEN1, CDC73, or CASR…

What is Rickets?

Rickets is a condition characterized by a defect in mineralization of the epiphyseal plates.  What is the Pathology of Rickets? The pathology of rickets is: -Etiology: The cause of rickets is vitamin D deficiency.  -Genes involved: PHEX, FGF-23, and VDR.…

What is Osteomalacia?

Osteomalacia is a disease characterized by the softening of the bones caused by impaired bone metabolism primarily due to inadequate levels of available phosphate, calcium, and vitamin D, or because of resorption of calcium.  What is the Pathology of Osteomalacia?…

What is Paget Disease of the Bone?

Paget disease of the bone is a condition involving cellular remodeling and deformity of one or more bones.  What is the Pathology of Paget Disease of the Bone? The pathology of Paget disease of the bone is: -Etiology: The cause…
Osteoporosis

What is Osteoporosis?

Osteoporosis is defined as low bone mineral density caused by altered bone microstructure, ultimately predisposing patients to low-impact, fragility fractures.  What is the Pathology of Osteoporosis? The pathology of osteoporosis is: -Etiology: The cause of osteoporosis is dietary factors.  -Genes…