Drug Induced Thrombocytopenia

What is Drug Induced Thrombocytopenia?

Drug induced thrombocytopenia is a disorder linked to immunologically mediated destruction of platelets after drug ingestion. What is the Pathology of Drug Induced Thrombocytopenia? The pathology of drug induced thrombocytopenia is: -Etiology: The cause of drug induced thrombocytopenia is certain…
Chronic Immune Thrombocytopenic Purpura

What is Chronic Immune Thrombocytopenic Purpura?

Chronic immune thrombocytopenic purpura is syndrome associated platelets coated with autoantibodies to platelet membrane antigens results in splenic sequestration and mononuclear macrophages phagocytosis commonly in adults. What is the Pathology of Chronic Immune Thrombocytopenic Purpura? The pathology of chronic immune…
Bleeding Disorders

What are Bleeding Disorders?

Bleeding disorders are condition with uncontrolled bleeding characterized with defect in the blood clotting process. Examples of bleeding disorders include:  Acute immune thrombocytopenic purpuraChronic immune thrombocytopenic purpuraDrug-induced thrombocytopeniaHIV-associated thrombocytopeniaThrombocytopenic purpuraUremic syndromeBernard-Soulier syndrome Glanzmann thrombastheniaClotting factor abnormalities
Hydrops Fetalis

What is Hydrops Fetalis?

Hydrops fetalis is a solemn fetal disorder defined as atypical buildup of fluid in two/more fetal compartments. What is the Pathology of Hydrops Fetalis? The pathology of hydrops fetalis is: -Etiology: The cause of hydrops fetalis is genetic factor. -Genes…
Thalasemia

What is A Thalasemia?

A thalasemia is a syndromes group of genetic anemias of varying clinical severity. What is the Pathology of A Thalasemia? The pathology of α thalasemia is: -Etiology: The cause of α thalasemia is gene mutation. -Genes involved: α-globin genes -Pathogenesis:…
B Thalassemia Minor

What is B Thalassemia Minor?

B Thalassemia minor is asymptomatic with mild or absent anemia. What is the Pathology of B Thalassemia Minor? The pathology of β- thalassemia minor is: -Etiology: The cause of β- thalassemia minor is a genetic mutation. -Genes involved: β-thalassemia gene.Heterozygotes…
B Thalassemia Major

What is B Thalassemia Major?

B thalassemia major is a severe transfusion dependent anemia with homozygous for β-thalassemia genes (β+/β+ or β0/β0). What is the Pathology of B Thalassemia Major? The pathology of β- thalassemia major is: -Etiology: The cause of β- thalassemia major is…
Thalassemia Syndromes

What are Thalassemia Syndromes?

Thalassemia syndromes is are a mixed group of hereditary disorders instigated by genetic lesions causing the reduced synthesis of α- or β-globin chain of HbA (α2β2). Examples of thalassemia syndromes include:  B thalassemia major B thalassemia minorA thalasemiaHydrops fetalis 
Sickle Cell Disease

What is Sickle Cell Disease?

Sickle cell disease is an inborn hemoglobinopathy, a disease characterized by the production of defective hemoglobin. What is the Pathology of Sickle Cell Disease? The pathology of sickle cell disease is: -Etiology: The cause of sickle cell disease is a…
Paroxysmal Nocturnal Hemoglobinuria

What is Paroxysmal Nocturnal Hemoglobinuria?

Paroxysmal nocturnal hemoglobinuria is a disorder resulting from acquired mutations in phosphatidylinositol glycan A (PIGA). What is the Pathology of Paroxysmal Nocturnal Hemoglobinuria? The pathology of paroxysmal nocturnal hemoglobinuria is: -Etiology: The cause of paroxysmal nocturnal hemoglobinuria is gene PIGA…