Increased Reticulin in Marrow in Myeloproliferative Disorder

Myeloproliferative Disorders Pathology Study Guide

Myeloproliferative Disorders Myeloproliferative disorders are neoplastic proliferation of myeloid cells. Myeloproliferative disorders typically occur in late adulthood (average age is 55-years-old). Myeloproliferative disorders are associated with: Leukocytosis (high white blood cell count) Hypercellular bone marrow In myeloproliferative disorders there is…
Microcytic Anemias

Microcytic Anemia Pathology Study Guide

Microcytic Anemias Anemia with MCV < 80 fL/m3 Microcytic anemias are due to decreased production of hemoglobin. Red blood cell (RBC) progenitor cells (erythroblasts) in the bone marrow are large and normally divide multiple times to produce smaller mature cells…
Prostate Adenocarcinoma

Prostate Pathology Study Guide

Prostate The prostate is a small, round gland in men that helps in the production of ejaculate. The prostate is located at the base of the bladder and surrounds the urethra. Since the prostate is anterior to the rectum, the…
Iron-deficiency Anemia, Peripheral Blood Smear

Anemia Pathology Study Guide

Anemia Anemia is characterized by the reduction in circulating red blood cell (RBC) mass. Anemia leads to a reduced flow of oxygen in the body.  Common signs and symptoms of anemia include: Hypoxia Weakness Light headedness Fatigue Dyspnea Pale conjunctiva…
Virchow’s Triad

Thrombosis and Embolism Pathology Study Guide

Thrombosis Pathologic development of an intravascular blood clot may result in a thrombus. Thrombosis may occur in arteries and/or veins. The deep veins in the leg below the knee are where they are most frequently found. Ante-mortem thrombosis is characterized…
THE PATHOLOGY OF HEMOSTASIS

Other Disorders of Hemostasis Pathology Study Guide

Heparin Induced Thrombocytopenia Heparin induced thrombocytopenia is the destruction of platelets that results from heparin therapy. Heparin induced thrombocytopenia (HIT) is an immune complication due to antibodies directed against complexes containing heparin and a platelet factor 4 (PF4). Platelet fragments…
Secondary Hemostasis

Secondary Hemostasis Pathology Study Guide

Secondary Hemostasis The whole point of secondary hemostasis is to stabilize the platelet plug. The main end product of the coagulation cascade is thrombin. Secondary hemostasis utilizes the coagulation cascade to stabilize the frail platelet plug. The fibrinogen in the…
Graves Disease

Endocrine Pathology Study Guide

The Endocrine System The body's ability to convert calories into energy that fuels cells and organs is one of several vital bodily processes that are regulated by the endocrine system, which is a network of glands responsible for producing and…
Mammosomatotroph Adenomas

Anterior Pituitary Gland Pathology Study Guide

Pituitary Adenoma Pituitary adenoma is a benign tumor of anterior pituitary cells. Pituitary adenomas may be functional meaning it is hormone-producing. Pituitary adenomas may be nonfunctional meaning it is silent. Nonfunctional tumors often present with mass effect. Bitemporal hemianopia may…
Cells of the Pituitary Gland

Posterior Pituitary Gland Pathology Study Guide

Posterior Pituitary Gland The hypothalamus produces oxytocin and antidiuretic hormone (ADH), which are subsequently sent by axons to the posterior pituitary for release. The distal tubules and collecting ducts of the kidney are affected by antidiuretic hormone (ADH), which encourages…